Breakdown of self/nonself recognition in cannibalistic strains of the predatory slime mold, Dictyostelium caveatum
نویسندگان
چکیده
Dictyostelium caveatum amebas feed upon both bacteria and the amebas of other cellular slime molds. The capacity to feed extensively upon other cellular slime molds is unique to D. caveatum amebas. They are able to phagocytose amebas larger than themselves by nibbling pieces of the cells until they are small enough to ingest. Here we report the isolation from previously cloned stock cultures of stable, cannibalistic strains of D. caveatum in which self/nonself recognition has broken down. Because of the extensive cannibalism, amebas of these strains do not complete multicellular development, and instead wander about for long periods while feeding upon each other. Although the cannibalistic behavior resembles that exhibited by the presumably diploid giant cells in the sexual cycle of other cellular slime molds, these strains are haploid and do not form macrocysts.
منابع مشابه
Choice of partners: sexual cell interactions in Dictyostelium discoideum.
Recognition of mating partners is of central importance in the sexual processes. In consideration that the most important function of sexuality is to shuffle genetic materials to generate wider variation of characters, mating among different genetic backgrounds is preferable. Wild isolates of cellular slime mold Dictyostelium discoideum are predominantly heterothallic, but homothallic ones also...
متن کاملVegetative Incompatibility and the Mating-Type Locus in the Cellular Slime Mold DICTYOSTELIUM DISCOIDEUM.
The genetic basis of vegetative incompatibility in the cellular slime mold, Dictyostelium discoideum, is elucidated. Vegetatively compatible haploid strains from parasexual diploids at a frequency of between 10(-6) and 10(-5), whereas "escaped" diploids are formed between vegetatively incompatible strains at a frequency of approximately 10(-8). There is probably only a single vegetative incompa...
متن کاملGenetic Diversity in Cellular Slime Molds: Allozyme Electrophoresis and a Monoclonal Antibody Reveal Cryptic Species among Dictyostelium discoideum Strains.
Cellular slime molds have been classified on the basis of a small number of descriptive criteria such as fruiting body color and morphology, and, in heterothallic species, by assignment to compatible mating groups. However, some isolates which are morphologically classified as conspecific do not fall into a simple mating-type classification; for example some are asexual or homothallic. An incre...
متن کاملA defined minimal medium for axenic strains of Dictyostelium discoideum.
A defined, minimal medium for the cellular slime mold Dictyostelium discoideum is reported.
متن کاملEvidence for a hierarchical mating system operating via pheromones in Dictyostelium giganteum.
Studies of four mating types of the cellular slime mold Dictyostelium giganteum revealed that each strain secrets its own sexual hormone to which each of the other three strains responds by forming macrocysts. Based on the ability to secrete or respond to hormone, the four strains can be arranged in a mating-type hierarchy.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of Cell Biology
دوره 102 شماره
صفحات -
تاریخ انتشار 1986